Alpha-melanocyte stimulating hormone as topical anti-inflammatory agent for the treatment of allergic contact dermatitis and eczema

A method is presented for treating an inflammatory skin disorder in a human comprising: topically applying to the skin a composition comprising alpha-melanocyte stimulating hormone (αMSH) or an αMSH analog in an amount effective to reduce skin inflammation in the human.

APPLICATION

A method is presented for treating an inflammatory skin disorder in a human comprising: topically applying to the skin a composition comprising alpha-melanocyte stimulating hormone (αMSH) or an αMSH analog in an amount effective to reduce skin inflammation in the human.

CLAIMS

A method of treating an inflammatory skin disorder in a human comprising: topically applying to the skin a composition comprising alpha-melanocyte stimulating hormone (αMSH) or an αMSH analogue in an amount effective to reduce skin inflammation in the human; wherein the composition comprises at least 30% 2-(2-ethoxyethoxy)ethanol and at least 5% NMP; wherein the αMSH analogue comprises KPV, dKPV, KPdV, dKPdV, KPT, or [Nle4,d-Ph7]αMSH; and wherein the αMSH or αMSH analogue is optionally N-acetylated on its N-terminus or C-amidated on its C terminus, or both, or circularized.

PATENT INFORMATION


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