ABSTRACT
The present disclosure provides compositions and methods for increasing the production of virus in vitro. Modified cells which are modified to eliminate or reduce as compared to a control cell the activity or expression of a Sterile a motif-domain containing protein 9 (SAMD9) polypeptide are provided. Methods of using these cells are also provided.
CLAIMS
1. A cell modified to eliminate or reduce as compared to a control cell the activity or expression of a Sterile α motif-domain containing protein 9 (SAMD9) polypeptide.