Classical cannabinoid metabolites and methods of use thereof

ABSTRACT

The present invention encompasses classical cannabinoid metabolites and uses thereof.

CLAIMS

1. An isolated classical cannabinoid glucuronide, wherein the classical cannabinoid is selected from the group consisting of CBG, CBC, CBL, CBV, and (±)-11-hydroxy-Δ9-THC (11-OH-THC).

2. A combination of a classical cannabinoid glucuronide and a compound selected from the group consisting of an analgesic, an anti-convulsant, an anti-inflammatory, an anti-anxiety compound, and an anti-emetic compound.
3. A method of detecting a classical cannabinoid glucuronide in a sample, the method comprising liquid chromatography followed by mass spectrometry, wherein the total chromatography run time is less than about eighteen minutes.
4. A combination of a classical cannabinoid glucuronide and a compound selected from the group consisting of an analgesic, an anti-convulsant, an anti-inflammatory, an anti-anxiety compound, and an anti-emetic compound, wherein the classical cannabinoid is selected from the group consisting of CBG, CBC, CBL, CBV, and (±)-11-hydroxy-Δ9-THC (11-OH-THC).
5. A method of detecting a classical cannabinoid glucuronide in a sample, the method comprising liquid chromatography followed by mass spectrometry, wherein the total chromatography run time is less than about eighteen minutes, wherein the classical cannabinoid is selected from the group consisting of CBG, CBC, CBL, CBV, and (±)-11-hydroxy-Δ9-THC (11-OH-THC).

PATENT INFORMATION