ABSTRACT
The present disclosure provides genetically modified animals and cells comprising a polynucleotide encoding human profilin1. Also provided are methods of assessing the effects of agents in genetically modified animals and cells comprising a polynucleotide encoding human profilin1.
CLAIMS
1 . A genetically modified animal comprising at least one exogenous nucleic acid, wherein the exogenous nucleic acid comprises a polynucleotide encoding a human profilinl protein.