ABSTRACT
The present disclosure relates to compositions and methods for improving the transplantation outcome and/or reducing immune response in a subject. The compositions comprise a DNA-PK inhibitor.
CLAIMS
1. A method of improving the transplantation outcome in a subject receiving an organ transplant, the method comprising administering to the subject a therapeutically effective amount of a composition comprising a DNA-PK inhibitor, wherein the DNA-PK inhibitor improves the transplantation outcome.